(6−11) Besides, they are ideal for single-shot measurements in point of care diagnostics as they are environmentally friendly and reduce the medical waste associated with disposable sensors and are usually low-cost. (3−5) The ability for real-time monitoring of parameters such as strain, pressure, temperature, pH, oxygen, and other specific biomarkers would expressively improve the information about tissue healing, early stage detection of postsurgical infection, and personalized treatments. With flexible form-factors, such sensor systems integrated on wearables or clothing could offer a hygienic route for monitoring of various physiological parameters. ![]() (1,2) They provide a unique opportunity for temporary medical implants for continuous body condition monitoring and in vivo sensing. Over the past decade, biodegradable sensors and electronic devices that naturally degrade or fully dissolve in their physiological environments have emerged as attractive alternatives for both invasive and noninvasive health monitoring. Promising perspectives for the advancement of future generation of biodegradable sensor systems are also presented. Lastly, key technological challenges are discussed for clinical application of biodegradable sensors, particularly for implantable devices with wireless data and power transfer. The recent trend and examples of biodegradable or bioresorbable materials-based sensors for body monitoring, diagnostic, and medical therapeutic applications are also presented. ![]() The discussion focuses on the dissolution rates and degradation mechanisms of materials such as natural and synthetic polymers, organic or inorganic semiconductors, and hydrolyzable metals. With this background, herein we present a comprehensive overview of the structural and functional biodegradable materials that have been used for various biodegradable or bioresorbable electronic devices. The eco-friendly sensor systems developed from degradable materials could also help mitigate some of the major environmental issues by reducing the volume of electronic or medical waste produced and, in turn, the carbon footprint. ![]() The implantable electronic systems made from such materials eliminate the need for extraction or reoperation, minimize chronic inflammatory responses, and hence offer attractive propositions for future biomedical technology. The recent advent of biodegradable materials has offered huge opportunity to transform healthcare technologies by enabling sensors that degrade naturally after use.
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